Going Back to Fundamentals: Three Marriageable Actions for Thalassemia and Carrier Population Management

Balearic archipelago: three islands, three beta-thalassemia population patterns.

The mutation spectrum of 175 β-thalassemia (β-thal) carriers, identified in pilot carrier screening on 22,713 individuals from Balearic Islands (Spain), is reported. The β(0) CD39 (C>T) mutation is the most frequent (61.1%), followed by β(+) IVS-I-110 (G>A) (12.0%), β(+) IVS-I-6 (T>C) and β(0) IVS-1-1 (G>A) (3.4% both) and eight other rare mutations (2.9-0.6%); with a distinct prevalence and di...

Back to Fundamentals: Equilibrium in Abstract Economies

We propose a new abstract definition of equilibrium in the spirit of competitive equilibrium: a profile of alternatives and a public ordering (expressing prestige, price or a social norm), such that each agent prefers his assigned alternative to all lower-ranked ones. The equilibrium operates in an abstract setting built upon a concept of convexity borrowed from Convex Geometry. We apply the co...

Back to Fundamentals: Abstract Competitive Equilibrium

We propose a new abstract definition of competitive equilibrium: a profile of alternatives and a public ordering (prestige, price or a social norm) such that each agent prefers his assigned alternative to all lower-ranked ones. The equilibrium operates in an abstract setting built upon a concept of convexity borrowed from Convex Geometry. The "magic" of linear equilibrium prices is put into per...

Reproductive behavior in carrier couples for transfusion-dependent thalassemia major: evaluation of knowledge, attitude and practice

Background and Purpose: Despite extensive research on family planning and education, reproductive behavior of high-risk couples for thalassemia remains a major concern among medical professionals. This study aimed to evaluate the knowledge and attitude of carrier couples for transfusion-dependent thalassemia major (TDTM). Methods: This case-control study was conducted 327 carrier couples for...

Beta-Thalassemia Carrier Detection by NESTROFT